[Ibogaine] Ibogaine in the Netherlands

simon loxton simonloxton at yahoo.co.uk
Fri Jan 23 08:38:09 EST 2009

Also the recent information on the death in Holland was not all that accurate; the patient was drinking and there were other issues. I have never heard of Sarah putting anyone at risk.

From: knowone knowwhere <kn0m0n3 at yahoo.co.uk>
To: The Ibogaine List <ibogaine at mindvox.com>
Sent: Thursday, 22 January, 2009 21:27:47
Subject: Re: [Ibogaine] Ibogaine in the Netherlands

I would just like to chim in that nobody has been as helpful as Sara with coming to terms with my own stuff.  And Sara hasn't made any money off of me.  Death can happen anytime anywhere to anyone, I hold Sara in the highest regard and would not hesitate dosing with her in the future.

--- On Mon, 19/1/09, Vector Vector <vector620022002 at yahoo.com> wrote:

From: Vector Vector <vector620022002 at yahoo.com>
Subject: Re: [Ibogaine] Ibogaine in the Netherlands
To: "The Ibogaine List" <ibogaine at mindvox.com>
Date: Monday, 19 January, 2009, 5:59 AM

Yeah that's Sara's house?

Much more in depth version of the same thing


New England Journal of Medicine

Volume 360:308-309        January 15, 2009        Number 3
Long-QT Syndrome Induced by the Antiaddiction Drug Ibogaine

    PubMed Citation

To the Editor: Anecdotal evidence suggests that ibogaine alleviates drug
craving and relapse of drug use in humans, as has been confirmed for animals.1
Ibogaine is currently used as an antiaddiction drug in alternative medicine. In
1993, the Food and Drug Administration approved a clinical trial in humans to
study those effects. The National Institute on Drug Abuse decided not to fund
this study because of safety issues.2,3

Ibogaine is a naturally occurring alkaloid with hallucinogenic and psychedelic
effects, derived from the bark of the root of the West African Tabernanthe iboga
plant and is used in Gabonian initiation ceremonies. At least 11 sudden deaths
were described after ibogaine use, in which the cause of death remained unclear
even after autopsy.4 It was hypothesized that ibogaine might dysregulate the
autonomic nervous system, causing sudden death.5

A 31-year-old American woman was admitted to our emergency department because
of a seizure-like attack after she had taken a single dose of 3.5 g of ibogaine
15% (usual dose, 2 to 6 g). She had not taken any other drugs or alcohol
concurrently with the ibogaine. Her medical history was unremarkable, and there
was no family history of cardiac-rhythm abnormalities. Besides nausea, she had
no specific symptoms to report. She had come to the Netherlands to receive
ibogaine as an alternative medicine for treatment-resistant alcohol addiction.

Electrocardiography showed a severe prolonged QT interval of 548 msec (QT
interval corrected for the heart rate, 616 msec) and ventricular
tachyarrhythmias during prolonged monitoring (Figure 1). Laboratory findings
revealed mild hypomagnesemia (magnesium level, 0.49 mmol per liter [1.2 mg per
deciliter]; reference range, 0.70 to 1.00 [1.7 to 2.4]), hypokalemia (potassium
level, 3.2 mmol per liter [12..5 mg per deciliter]; reference range, 3.8 to 5.0
[14.9 to 19.5]), and a normal serum osmolal gap (3.1 mOsm per kilogram;
reference value, <10). Despite rapid correction of the electrolyte levels,
the QT interval remained prolonged. During admission to the intensive care unit,
with no further doses of ibogaine given, the QT interval normalized at 42 hours
after presentation. The patient was subsequently discharged, in good condition.

 In this case, ibogaine use was associated with severe lengthening of the QT
interval and ventricular tachyarrhythmias, which normalized after 42 hours.
These findings are suggestive of a causal relation. The electrolyte imbalance
may also have played a role. The previously described sudden deaths may thus
have been caused by cardiac-rhythm abnormalities induced by QT-interval
lengthening, ventricular tachyarrhythmias, or both.

At the doses currently used, ibogaine can lead to serious cardiac-rhythm
abnormalities. The use and possible future trials of the drug should be
permitted only under strict medical observation and continuous
electrocardiographic monitoring.

Dianne W.M. Hoelen, M.D. 
Wilko Spiering, M.D., Ph.D. 
Gerlof D. Valk, M.D., Ph.D. 
University Medical Center Utrecht 
3584 CX Utrecht, the Netherlands 
g.d.valk at umcutrecht.nl


He D-Y, McGough NNH, Ravindranathan A, et al. Glial cell line-derived
neurotrophic factor mediates the desirable actions of the anti-addiction drug
ibogaine against alcohol consumption. J Neurosci 2005;25:619-628.. [Free Full
Vastag B. Addiction treatment strives for legitimacy.. JAMA 2002;288:3096,
Vastag B. Addiction research -- ibogaine therapy: a `vast, uncontrolled
experiment.' Science 2005;308:345-346. [Erratum, Science 2005;308:1260.]
[Free Full Text]
Lotsof HS, Wachtel B.. Manual for ibogaine therapy: screening, safety,
monitoring & aftercare. Second revision. The Ibogaine Dossier, 2003.
(Accessed December 22, 2008, at http://www.ibogaine.org/manual.html.)
Maas U, Strubelt S. Fatalities after taking ibogaine in addiction treatment
could be related to sudden cardiac death caused by autonomic dysfunction. Med
Hypotheses 2006;67:960-964. [Medline]

----- Original Message ----
From: Mindvox <mindvox at lunartproductions.com>
To: The Ibogaine List <ibogaine at mindvox.com>
Sent: Monday, January 19, 2009 5:22:25 AM
Subject: [Ibogaine] Ibogaine in the Netherlands

Near-fatal treatment in the Netherlands...



    'Afkickmedicijn’ ibogaïne veroorzaakt hartritmestoornis
Bron(nen): UMC Utrecht

Smart drug en ‘afkickmedicijn’ ibogaïne kan dodelijke hartritme
stoornissen veroorzaken. Dit schrijven artsen van het UMC Utrecht in een case
report in het tijdschrift New England Journal of Medicine van 15 januari. Ze
verklaren daarmee als eerste de schadelijkheid van het omstreden middel.

In het case report beschrijven internisten een 31-jarige Amerikaanse vrouw die
op de spoedeisende hulp van het UMC Utrecht kwam nadat zij onwel was geworden na
het gebruik van ibogaïne. Dit had zij gebruikt om van haar alcoholverslaving af
te komen. Tijdens haar behandeling op de spoedeisende hulp kreeg zij een
ernstige hartritmestoornis. Het duurde bijna twee dagen voordat de
hartritmestoornis was verdwenen. Het verband tussen het gebruik van ibogaïne en
het optreden van de hartritmestoornis ligt volgens de artsen van het UMC Utrecht
voor de hand.

Ibogaï vrij verkrijgbaar
Ibogaïne is in een beperkt aantal landen, waaronder Nederland, vrij
verkrijgbaar. Het wordt gebruikt als smart drug. Daarnaast claimen alternatieve
genezers en sommige artsen dat een eenmalige dosis van het middel mensen van hun
drugs- of alcoholverslaving af kan helpen. Voor dit effect bestaan weliswaar
wetenschappelijke aanwijzingen bij proefdieren, grootschalige onderzoeken bij
mensen ontbreken echter. Onderzoek naar ibogaïne is lastig omdat het middel
levensgevaarlijk kan zijn. Het is bekend dat gebruikers van ibogaïne soms
overlijden. Waardoor dat komt was tot nu toe onduidelijk.

Hulpmiddel afkicken
“Ibogaine wordt momenteel in Nederland gebruikt als hulpmiddel bij het
afkicken in situaties zonder medisch toezicht waardoor het juist
levensbedreigend kan zijn”, concludeert internist-endocrinoloog dr. Gerlof
Valk van het UMC Utrecht, één van de internisten betrokken bij de opvang van
de patiënt. “De risico’s voor de gezondheid gelden zowel voor de toepassing
als smart drug, maar ook voor het gebruik als afkickmiddel. Wij vinden dat
ibogaïne alleen onder medisch toezicht gebruikt mag worden voor therapeutische

De artsen hebben de ibogaïne-vergiftiging gemeld bij de Inspectie voor de


    Detox-medicine ibogaïne cause heart rhythm impairment
Source (nen): UMC Utrecht

Smart drug and `detox-medicine' ibogaïne can cause deadly heart rhythm
impairments. This letter doctors of the UMC Utrecht in a case report in the
illustrated magazine New England Journal or Medicine of 15 January. They explain
with that as first the harmfulness of the controversial means.

In case report internists describe a 31 year old American woman who came on the
emergency service of the UMC Utrecht after she had become indisposed after the
use of ibogaïne. This had they uses to descend of its alcohol addiction. During
its treatment on the emergency service she got a serious heart rhythm
impairment. It lasted almost two days before the heart rhythm impairment had
disappeared. The link between the use of ibogaïne and acting the heart rhythm
impairment lies according to the doctors of the UMC Utrecht for the hand.

Ibogaï rather available
Ibogaïne are a number of countries limited in, among which the Netherlands,
rather available. It is used as smart drug. Moreover alternative healers claim
and some doctors that a one-off amount of the means people of their drugs or
alcohol addiction finished can help. For this impact indeed scientific
indications exist at test animals, large-scale researches at people are lacking
however. Study into ibogaïne is cumbersome because the means can be perilous.
It has been confessed that users of ibogaïne die sometimes. How that comes were
so far unclear.

Appliances kick the habit
Ibogaine are at present used in the Netherlands as appliances at kick the habit
in situations without medical supervision as a result of which it can be
correctly life-threatening, internist endocrinoloog conclude dr. Gerlof falcon
of the UMC Utrecht, one of the internists involved at the relief of the patient.
The risk for health applies both for the application and smart drug, but also
for the use as afkickmiddel. We find that ibogaïne can be only used under
medical supervision for therapeutic aims.

The doctors have communicated ibogaïne poisoning at the inspection for the
health care.


Afkickdrug kan dodelijk uitpakken

De iboga-wortel, een populair alternatief middel tegen verslaving, kan
dodelijke hartritmestoornissen geven. In Utrecht is een vrouw er bijna aan

Een 31-jarige Amerikaanse vrouw heeft ternauwernood een vergiftiging met een
extract van de Afrikaanse iboga-wortel overleefd. Ze was speciaal naar Nederland
gekomen om zich met dit sterk hallucinogene middel, ibogaïne, te laten
behandelen tegen haar alcoholverslaving.

De drug, in de meeste landen verboden, is in Nederland toegestaan. Hij wordt in
het alternatieve circuit gebruikt, naar verluidt met groot succes. Met één
dosis ibogaïne raak je een paar dagen compleet van de wereld. Als je wakker
wordt, ben je clean, zo wil het verhaal.

Maar bij de Amerikaanse liep het anders. Ze belandde op de intensive care van
het Universitair Medisch Centrum Utrecht, met ernstige hartritmestoornissen die
haar fataal dreigden te worden. Pas na twee dagen herstelde het hart zich,
melden haar artsen vandaag in het vakblad The New England Journal of Medicine.
Ze hebben de Inspectie voor de Gezondheidszorg gewaarschuwd.

„Op zich kunnen we niet met zekerheid vaststellen dat ibogaïne de oorzaak
van de klachten was”, relativeert de behandelend internist Gerlof Valk.
„Maar de aanwijzingen zijn sterk. De klachten begonnen kort na de inname en
verdwenen een paar dagen later. De patiënte had verder geen middelen gebruikt.
Lichamelijk konden we ook geen andere verklaring vinden.”

De artsen noemen de vondst belangrijk omdat deze nieuw licht werpt op de
raadselachtige dood van elf eerdere ibogaïne-gebruikers. Zelfs een autopsie
heeft in die gevallen geen duidelijkheid gebracht over de doodsoorzaak. Het
bleef daardoor onzeker of de drug de boosdoener was, of misschien de alcohol of
iets anders wat de slachtoffers tegelijkertijd hadden ingenomen.

De nieuwe waarneming, waarbij de drug als het ware ’op heterdaad’ is
betrapt, maakt het volgens de Utrechtse artsen een stuk aannemelijker dat het
middel zelf riskant is. Ze pleiten er daarom voor om de stof voortaan alleen nog
onder medische begeleiding en onder permanente hartbewaking toe te dienen. Dat
zou het gebruik door alternatieve therapeuten sterk bemoeilijken.

Overigens is het de vraag of ibogaïne echt zo fabelachtig tegen verslaving
werkt als alternatieve therapeuten beweren. „Op internet zijn allerlei
filmpjes te zien van mensen die dankzij ibogaïne van hun verslaving zijn
afgekomen”, zegt Valk. „Maar hard wetenschappelijk bewijs ontbreekt.” Goed
onderzoek met patiënten is nooit gedaan, onder meer vanwege twijfel over de
veiligheid. Wel is gekeken naar verslaafde ratjes; die toonden zich dankzij
ibogaïne inderdaad minder afhankelijk van morfine, cocaïne of alcohol.

Hoeveel mensen zich tot nu toe met de drug hebben laten behandelen, is
onduidelijk. Het tv-programma ’Nova’ repte in 2006 van duizenden mensen
wereldwijd, en van ruim 220 patiënten die door de Nederlandse therapeute Sara
Glatt waren geholpen. In de uitzending stelde een deskundige dat de reguliere
verslavingszorg met ibogaïne een grote kans liet liggen.

Behalve als afkickmedicijn gebruiken sommigen de iboga-wortel als smart drug,
omdat hij zo’n intense en langdurige roes veroorzaakt. Die diepe trance is ook
de reden waarom Afrikaanse stammen de plant inzetten tijdens riten.


Detox-drug can unpack deadly

Iboga-root, the popular alternative means against addiction, can give deadly
heart rhythm impairments. In Utrecht a woman is there almost to deceased.

A 31 year old American woman a poisoning with an extract of African iboga-root
has just survived. She especially to the Netherlands had come with this strongly
hallucinogenic means, ibogaïne, let treat itself against its alcohol addiction.

The drug, prohibited in the most countries, in the Netherlands it has been
permitted. He is used in the alternative circuit, according to reports with
large success. With one amount of ibogaïne touch you a couple days completely
of the world. If you become awake, be you clean, this way it wants tale.

But at American it ran differently. She ended up on the intensive care of the
university medical centre Utrecht, with serious heart rhythm impairments which
threatened become its fatally. Just after two days repaired the heart, its
doctors communicate themselves The New England Journal or Medicine today in the
profession booklet. They have warned the inspection for the health care.

„In itself cannot determine we with certainty that ibogaïne were the cause
of the complaints, relativise the treating internist Gerlof falcon. „But the
indications are strong. Days started the complaints later shortly after
ingestion and disappeared a couple. The patient had further used no resources.
Physically we could find other declaration also no.

The doctors call the find important because these throw slightly new on
enigmatic dead of eleven earlier ibogaïne users. Even an autopsy has which
fallen no clarity brought concerning the cause of death. It remained uncertainly
as a result, or the drug the cause was, or perhaps the alcohol or something else
what the victims had taken at the same time.

New perception, where the drug as it were has been caught, makes it according
to the Utrechtse doctors a piece more plausible that the means himself is risky.
They plead for this reason to administer the substance as of now only still
under medical accompaniment and under permanent heart guarding. That it strongly
would hamper use by alternative therapists.

Moreover it is the question if ibogaïne work really this way fabulous against
addiction such as alternative therapists claim. „On Internet are all kinds of
see small films of people who have descended thanks to ibogaïne of their
addiction, say falcon. „But rapidly scientific proof are lacking. Well
research with patients has been never done, including because of doubt
concerning the security. However, it has been looked at to addictive little
rats; those showed themselves thanks to ibogaïne indeed less dependent on
morphine, cocaine or alcohol.

How many people itself so far with the drug have let treat, is unclear. The
tv-programma Nova' mentioned in 2006, of thousands of people worldwide, and
of wide 220 patients who had been helped by the Dutch therapist Sara Glatt. In
the retransmission put to an expert to that to the regular care and treatment of
drug addicts with ibogaïne to a large chance let lie.

Except as detox-drug uses some iboga-root as smart drug, because he causes such
a intense and long-term fuddle. That deep trance is also the reason why descends
African the plant uses during rites.

Translation is done through an online web translator, so as you just read, it
is not very accurate...

Best Wishes,

Ben De Loenen

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