[Ibogaine] chronic pain thing

Steve Coss coss at blodgettsupply.com
Sat Feb 16 07:00:36 EST 2008

It is a bitch when you have chronic pain (long story but lots of nerve
damage from bungled operation on back)coupled with the fact that you are
a product of the sixty's and as such, at least in my case abused every
substance known to man. If I was smart I would only get a weeks worth of
meds at a time. But I'm not :)
They do make a antidepressant called Cymbalta (sp?) that is supposed to
be excellent for chronic pain people.
Good Luck and God Bless'

-----Original Message-----
From: ibogaine-bounces at mindvox.com [mailto:ibogaine-bounces at mindvox.com]
On Behalf Of Preston Peet
Sent: Saturday, February 16, 2008 6:44 AM
To: DrugWar at mindvox.com; ibogaine at mindvox.com
Subject: [Ibogaine] chronic pain thing

perhaps there's more going on with my depression/ups/downs issues than
simply bad choices and/or addictive tendencies. Always enjoy finding
something that helps me feel that perhaps I'm not such a total dick
after all, or at least gives me hope that's the case.
FRIDAY, Feb. 8 (HealthDay News) -- Chronic pain can disrupt brain
function and cause problems such as disturbed sleep, depression, anxiety
and difficulty making simple decisions, a U.S. study finds.
Researchers at Northwestern University's Feinberg School of Medicine in
Chicago used functional MRI to scan brain activity in people with
chronic low back pain while they tracked a moving bar on a computer
screen. They did the same thing with a control group of people with no
In those with no pain, the brain regions displayed a state of
equilibrium. When one region was active, the other regions calmed down.
But in people with chronic pain, the front region of the cortex mostly
associated with emotion "never shuts up," study author Dante Chialvo, an
associate research professor of physiology, said in a prepared
This region remains highly active, which wears out neurons and alters
their connections to each other. This constant firing of neurons could
cause permanent damage.
"We know when neurons fire too much they may change their connections
with other neurons or even die, because they can't sustain high activity
for so long," Chialvo said.
"If you are a chronic pain patient, you have pain 24 hours a day, seven
days a week, every minute of your life. That permanent perception of
pain in your brain makes these areas in your brain continuously active.
This continuous dysfunction in the equilibrium of the brain can change
the wiring forever and could hurt the brain," Chialvo explained.
These changes "may make it harder for you to make a decision or be in a
good mood to get up in the morning. It could be that pain produces
depression and the other reported abnormalities, because it disturbs the
balance of the brain as a whole," he said.
The study was published in the Feb. 6 issue of The Journal of
Chialvo said the findings show that, along with finding new ways to
treat pain, it's also important to develop methods to evaluate and
prevent disruption of brain function caused by chronic pain.
More information
The American Academy of Family Physicians has more about chronic pain.

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