[Ibogaine] dopamine 4 neuron

Douglas Fraser doug_fraser at microcinema.com
Mon Dec 29 16:04:11 EST 2008

d4 involved in addiction is an interesting idea, but my intuition 
(IANAN(euroscientist)) says only for a certain of addiction and / or only 
peripherally.  One person I knew said her problem stemmed from always 
wanting "more, more, more", but I would say she hadn't yet begun the 
psychological journey and thus what might lie beneath that always wanting 
more stimulation

I would definitely say d4 is involved in whether one is attracted to or 
even can handle the psychedelic experience (versus other types of drugs)  A 
lot of people can not handle the amount of novelty psychedelics throw up, 
so as Leary said, they become psychotic without even taking it.

tangential would be a link to the genome analysis / DNA test thing company 
that the wife of a Google founder is involved in - you can your own genome 


Luke Christoffersen wrote:
> On wikipedia it says d4 is involved in novelty seeking. That would
> seem to make it involved in human curiousity and learning.
> http://en.wikipedia.org/wiki/Dopamine_receptor_D4#Novelty_seeking
> On Fri, Dec 26, 2008 at 4:02 PM, simon loxton <simonloxton at yahoo.co.uk> wrote:
>> I was watching a documentary on the human genome. The researcher had based
>> his research in Iceland for obvious reasons. He found among other things
>> that an extended dopamine 4 neuron had an influence in thrill seeking or
>> extreme sports. This was interesting and I wondered if the same or some
>> thing similar could be suggested in the majority of people with addiction?

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