[Ibogaine]Questions about LAMM and Ibogaine

Krista Vaughan krista.vaughan at gmail.com
Mon Oct 2 21:55:53 EDT 2006

Howard I know you hate Dr. Mash and I understand your viewpoint, but
what you say doesn't jibe with her submitting grants to NIDA and
having all of them shot down and not being able to get funding. If
nobody is paying for the studies to continue, how is it that she's
supposed to do them?


On 10/2/06, HSLotsof at aol.com <HSLotsof at aol.com> wrote:
>  In a message dated 10/2/06 6:29:48 PM, BiscuitBoy714 at aol.com writes:
> In a message dated 9/23/2006 2:48:57 P.M. Eastern Standard Time,
> vector620022002 at yahoo.com writes:
>  Levo alphacetylmethadol (LAAM), for example, was a
>  Schedule I drug when it was developed as a narcotic treatment drug.
>  However, the potential for brain damage in humans, as well as the
>  deaths of some clients undergoing ibogaine "treatment" in Europe,
>  raises concerns regarding future administration of Ibogaine to humans
>  I've been reading and getting rid of old mail and came across this. Why
> would LAAM get approved so fast and not Ibogaine. It is my understanding
> that there was a lot of deaths behind the administering of LAMM. I know
> personally a couple of guys in KY that damn near died from this stuff. I
> know that it is no longer being used in KY, what about the rest of the US?
> It's like a longer acting methadone isn't it? Has anyone ever been treated
> with Ibogaine treatments for LAMM? I'm curious and any input is welcomed
> here.       Randy
>  LAAM was approved because it was developed by the National Institute on
> Drug Abuse (NIDA).  It took them about twenty years.  At one point all of
> their data was disallowed by the FDA because the contract research
> organization they were using was found to be guilty of some FDA submission
> offense so all of that company's data was disallowed including that for
> LAAM.      I haven't probably gotten that exactly right but, close enough.
> Once LAAM was approved after some years they found that it had associated
> cardiac fatalities and the manufacturer discontinued it as it was not
> exactly a money maker. I am not sure whether anyone on LAAM was ever treated
> with ibogaine.  My guess would be not unless they were first transferred to
> a short acting narcotic, a common practice on St. Kitts to my understanding.
> What is interesting is that LAAM is an example of a schedule I drug that was
> rescheduled.  This is most likely what would happen with ibogaine if it is
> ever moved through the FDA approval process. The FDA approved an ibogaine
> study at the University of Miami in 1993 but the work was abandoned when D.
> Mash opted to open St. Kitts rather than continue the work.
>  Howard

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